Use a reputable anti-malware engine (like Malwarebytes or Norton Power Eraser).
If you used a USB drive recently, format it on a non-infected machine (preferably Linux or Mac) to kill the autorun.inf file.
Before Windows loads, hold the key while selecting Power > Restart .
Press Win + R , type regedit , and navigate to:
Pilleuz can modify proxy settings to intercept traffic. Reset your browser settings to default.
If the automated tools don't catch everything, check these common Pilleuz persistence points: