Flow Cytometry In Neoplastic Hematology Morphol... Now
It detects "CD markers" (Clusters of Differentiation). CD34: Signals a primitive, immature cell. CD19/CD20: Confirms a B-cell lineage. CD13/CD33: Points toward myeloid involvement. The Synthesis: A Final Diagnosis
The microscopic world of hematology is often a battle between what we see and what is actually there. In the diagnosis of neoplastic diseases, the "story" is one of collaboration between traditional morphology and the high-tech precision of flow cytometry. The Visual Clues (Morphology) Flow Cytometry in Neoplastic Hematology Morphol...
The true power lies in the overlap. A pathologist might see "monomorphous medium-sized blasts" (Morphology) and use Flow Cytometry to confirm they are actually "CD10+ B-lymphoblasts." It detects "CD markers" (Clusters of Differentiation)