If the mouse stops working suddenly while playing, try these quick steps: I'm having trouble with san andreas and my mouse. : r/GTA
The most effective way to solve this issue permanently is to use a community-made fix that replaces the bugged input method with modern raw input. If the mouse stops working suddenly while playing,
Open (Ctrl+Shift+Esc) and go to the Details tab. Right-click gta_sa.exe and select Set Affinity . Uncheck All Processors and select only CPU 0 . Right-click gta_sa
Return to the game. You may need to repeat this every time you launch the game unless you create a custom batch file to automate it. You may need to repeat this every time
If your mouse is stuck or clicking doesn't work in Grand Theft Auto: San Andreas on Windows 10, it is likely because the game was not designed for modern multi-core processors or newer DirectInput versions.
: Drag and drop the downloaded dinput8.dll file into the main folder where gta_sa.exe is located.