The title refers to a high-stakes medical mystery where Dr. Gregory House must solve a case involving a set of triplets whose identical DNA makes diagnosing their divergent symptoms a nightmare . The Case of the Mirror Triplets
: Cuddy pressures House to find a solution before Maya’s lungs fail completely. Meanwhile, House is distracted by Wilson, who has started "triplet-dating" (dating a woman who is also a triplet), leading to a series of pranks about identity and individuality. The "Eureka" Moment Dr. House: 2Г—3
House orders an aggressive chelation therapy tailored to each sister's specific organ failure. As they recover, the sisters realize that their drive for "identical perfection" nearly killed them. The episode ends with House alone in his office, spinning a juggling ball—reflecting on how even "identical" things are never truly the same. The title refers to a high-stakes medical mystery where Dr